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Depresses heart, respiration and blood pressure, lowers temperature. Cyanosis and collapse. Increased susceptibility to cold. Destroys red blood corpuscles; pallor.

Head.--Enlarged sensation. Fainting. Moral depravity.

Eyes.--Pallor of optic discs, contracted visual field and shrinking retinal vessel; mydriasis.

Heart.--Weak, irregular, with blue mucous membranes, albuminuria, oedema of feet and ankles.

Relationship.--Compare: Antipyrin.

Dose.--Used as a sedative and antipyretic for various forms of headache and neuralgia in doses of one to three grains. For the homeopathic indications use the third potency.