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Cocculus Indicus. N. O. Menispermaceae. A tincture is prepared from the powdered seeds, which contain a crystallisable principle Picrotoxine (which see), a powerful poison.

Clinical.-Anger, effects of. Bones, affections of. Cerebro-spinal meningitis. Chorea. Colic. Convulsions. Debility. Faintness. Fear, effects of. Haemorrhoids. Headache. Hernia. Intermittent fever. Knee, weakness of; cracking in. Memory, weak. Mental excitement, effects of. Menstrual headache. Menstruation, painful. Overstrain, bodily or mental. Palpitation. Paralysis. Parotitis. Phthiriasis. Rheumatism. Riding in carriage, effects of. Sea-sickness. Sleep, affections from loss of. Somnolence. Spasms. Spinal irritation. Tympany. Vertigo. Vomiting.

Characteristics.-Cocculus has been used from ancient times as a poison for stupefying fish, and making them easy to catch. Correspondingly we find it produces great disturbance of the sensorium in human beings, and all the symptoms of intoxication. It is commonly used as an adulteration of beer to heighten its intoxicating properties. A very characteristic symptom is a sensation of hollowness or emptiness in the head or other parts. Allied to this is a sense of lightness of body. Another characteristic is an opening and shutting sensation, especially in the occiput. Along with the vertigo is nausea and vomiting which bring it into close relation with sea-sickness and carriage-sickness. Coccul. corresponds perfectly to the sensitive condition caused by loss of sleep and night-watching, and is the first remedy to think of for removing this. "Irritable weakness" is a leading note in the Cocculus effects. The Cocculus patient is very sensitive to fear, anger, grief, and all mental disturbances; also to noise and touch. Enlargement of liver after anger. Easily startled. Fear of ghosts and spectres. Stinging pains, stitches, constriction; in the hands a pithy feeling. Many symptoms are < at menstrual period; piles during menses. Cocculus has cured a case of delirium at onset of menses during first and second days; the patient said, "I always see something alive, on wall, floor, chairs, or anywhere, always rolling, and will roll on me." Cocculus is suited to persons of mild and sluggish temperament; light-haired persons; hypochondriacal, timid, fearful, and nervous persons. Other prominent features of Coccul. are: Paralytic pains, or pains as of dislocation. Paralytic weakness; lax-muscles. "Weakness of neck muscles with heaviness of head." Sensation as if single parts had gone to sleep. Immovability of parts affected. Of localities, the right hypochondrium (especially liver), inner hypogastrium, inner forehead, back, upper arm, and bones of arm are chiefly affected. This has been verified: "Spasmodic, flatulent colic, about midnight, flatus passed without relief," recurring several nights; promptly cured by Coccul. 3x. Lippe cured a case of enlargement of the liver after parturition, the indication being "the liver was more painful after anger." The sensitiveness to touch is very great and serves to indicate Cocculus in preference to other remedies in many affections where this is pronounced, in articular rheumatism, in ulcers, in neuralgic affections of bones. The least jar is unbearable (travelling by land or sea). < By touch, pressure, or jar. < From motion generally; moving body; rising from bed; bending over or stooping. < Kneeling; walking; swallowing saliva. Sitting > some symptoms. Many symptoms are < evening and night, especially about midnight and 1 a.m. Sensitive to air either hot or cold. Longs for cold drinks, but eating or drinking anything cold = tearing in limbs. < Open air. < From sun. < By warmth of bed. > In a room. A decoction of Cocculus is a domestic remedy used locally for destroying head- or body-lice.

Relations.-Antidoted by: Camph., Cham., Cupr., Ign., Nux v., Staph. It antidotes: Alcohol, Tobacco, Cham., Cup., Ign., Nux v., and the fever of Thuj. Incompatible with: Caust., Coffee. Compatible: Follows well Aco. (endocarditis with fearfulness); Cham., Nux, Ign. Compare: Aco., Act. r.; Ant. c. (gastralgia), Agar. (somnolency), Ant. t., Ars., Bell., Calc., Carb. v. (parotitis), Cham., Coff., Cupr., Ign. (headache), Ip., Iod., Lach., Merc., Mosch., Nitr., Nux mos. (somnolency), Oleand., Petr., Puls. (headache), Rhus, Sabi., Sassafras, Scutel., Silic., Stram., Tab., Val., Ver. In effects from noise, Nux, Nit. ac. Sense of lightness, Asar., Can. ind., Calc., Gels., Sticta, Sil., Thuj.; menstrual sick headache, Lac. def.; fear of ghosts, Aco., Ars., Bro., Carb. v., Lyc., Pho., Pul., Sul., Zn. Umbilical hernia, Nux (without urging, Bry., Nat. mur., Ver.); < from kneeling, Mag. c., Sep.; nausea constant, Ip., Kali c., Sul., Ign., Acet. ac.; uterine spasm, dysmenia, dark flow, Ign. (Coccul. is distinguished by having weak, lame feeling in small of back; as if about to be paralysed; trembles on beginning to walk); weak from talking, Ver., Sul., Calc.; functional paralysis from fatigue or mental emotions, Ign., Pho., Nat. m., Collins.; in occipital headache, Gels., jug. c. Weakness of neck muscles, Ant. t.; > putting head back, Seneg. (